Psilocybine

J’ai utilisé la psilocybine en chimio-immunothérapie, pour garder le moral au mieux. Je ne savais pas qu’elle protégeait aussi le cerveau des dommages lors de la chimio.
voici une nouvelle étude.

Psilocybin prevents chemotherapy-induced peripheral neuropathy through mitochondrial trafficking preservation

Editor’s summary

Chemotherapy-induced peripheral neuropathy (CIPN), one of the most debilitating side effects of some cancer therapies, is a painful condition with no known remedy and is thus a major cause of treatment discontinuation. Heles et al. reported that prophylactic treatment with the natural psychedelic psilocybin prevented the development of CIPN in mouse models (see the Perspective by Maiarú). Mechanistically, psylocibin acted both peripherally and centrally through two independent mechanisms: reducing pain perception and protecting peripheral sensory neurons. Psychedelics might offer an effective therapeutic approach for preventing CIPN. —Mattia Maroso

https://www.science.org/doi/10.1126/science.aec6116